MECHANOCHEMICAL CONDITIONS PROMOTE SELECTIVE CROSS-COUPLING

摘要

Mechanochemistry is an attractive field for chemists, since it provides a green and sustainable route to valuable products. Compared to liquid-phase chemistry, it has been largely underexplored, with some unique reaction patterns discovered. This uncharted chemical space presents solutions for conventional liquid-phase reactions. For example, the design of new and generally applicable strategies for Suzuki-Miyaura cross-couplings that improve and control monoarylation selectivity remains in high demand.