Organomediated Morita-Baylis-Hillman Cyclization Reactions

摘要

Continuing development in synthetic organic chemistry relies on discovering new,high yielding,selective reactions.The Morita- Baylis-Hillman reaction,originating from both German and Japanese patents,is an organocatalytic reaction involving coupling of the a-position of activated alkenes with carbonyl electrophiles under the catalytic influence of a nucleophilic species,providing a simple and convenient method for the synthesis of interesting densely functionalized molecules.