Rhenium-Catalyzed Insertion of Aldehyde into a C-H Bond:Synthesis of Isobenzofuran Derivatives

摘要

Chemical transformations via catalytic C-H bond activation are expected to become a powerful tool in organic synthetic chemistry.Ruthenium and rhodium complexes have been commonly used for C-H bond activation,which is usually followed by the insertion of unsaturated molecules.However,the unsaturated molecules have been mainly limited to nonpolar ones,such as olefins and acetylenes.