Versatile,Fragrant,Convertible Isonitriles

摘要

Isonitriles are versatile functionalities in organic synthesis.They are active participants in radical reactions,and as such have played crucial roles in several total and combinatorial syntheses.They can substitute for the gaseous and poisonous carbon monoxide in organometallic transformations,they are polymerized to helical polymers,and they are key to several multicomponent processes,such as the Passerini and Ugi reactions,of high interest in combinatorial chemistry.