New Class of Nucleophiles for Palladium-Catalyzed Asymmetric Allylic Alkylation.Total Synthesis of Agelastatin A

摘要

Metal-catalyzed allylic alkylations increase in importance as a synthetic method as the ability to expand their scope increases.A major feature of this method is its applicability for formation of a broad array of bond types,including carbon-carbon and carbon- heteroatom bonds.The importance of nitrogen-containing bioactive molecules directs special attention to the formation of carbon-nitrogen bonds.