Oxidative Pd(ii)-catalyzed C-h Bond Amination To Carbazole At Ambientrntemperature

摘要

The ubiquity of aromatic C-N bonds in organic molecules has made the development of novel amination methodologies an important objective for chemical synthesis. Until recently, traditional methods for diaryl-amine bond construction routinely focused on variations of Cu-mediated Ullmann coupling between an aryl halide and an aniline. However, these processes can sometimes be problematic due to harsh conditions, therefore restricting their utility in complex molecule synthesis applications.