Photosensitized 2 + 2 Cycloaddition Reaction Using Homochirality Generated by Spontaneous Crystallization

摘要

Mirror symmetry breaking influenced by a chiral crystalline environment can be considered an attractive methodology for obtaining optically active compounds from achiral compounds; this methodology is recognized as the absolute asymmetric synthesis. Many examples of the solid-state photoreaction leading to optically active materials have been successfully demonstrated.2 Recently, a new methodology using the molecular homochirality in the crystal as a source of homochirality in solution was explored.