Pd(II)-Catalyzed Hydroxyl-Directed C-H Activation/C-O Cyclization:Expedient Construction of Dihydrobenzofurans

摘要

A Pd(II)-catalyzed C-H activation/C-O cyclization reaction directed by a proximate hydroxyl group has been developed. This reaction provides a new method for constructing dihydrobenzofurans, including spirocyclic analogues, a process that is potentially applicable to natural product synthesis.