CATCHING CANCER CELLS WITH LOGIC AND DNA

摘要

Weihong Tan and colleagues have developed a DNA-based system that uses Boolean logic gates to profile the expression of multiple cell surface markers. It could be used to identify and deliver therapeutics to cancer cells with high specificity (DOI: 10.1021/ja509263k). Many cancer cells aberrantly express certain cell surface receptors. To accurately diagnose and treat cancer, researchers want to be able to identify these cells by gauging the expression of multiple cell surface biomarkers simultaneously.