Solid supported synthesis of 2-mercaptobenzimidazole derivatives using microwaves

摘要

2-Mercaptobenzimidazole(MBI) derivatives having substituent at either nitrogen or sulphur of a thioamide ring exhibit biological activity. MBI derivatives were synthesized in moderate to high yields in a short time to give pure required products by using solid support such as silica gel / neutral alumina / fly ash under microwave assisted solventless conditions.