A new and versatile allylic alcohol anion and acyl β-anion equivalent for three-carbon homologations

摘要

There are many reagents useful for the extension of organic molecules by three carbons with some functional- ity at the new terminus. However, to the best of our knowledge, the possibility of introducing an allylic alcohol residue is restricted to only a few examples despite its potential utility in the synthesis of complex organic molecules, like saccharides and related polyhydroxylated natural products, e.g., via asymmetric epoxidation or dihydroxylation.