Al-isopropoxydiisobutylalne. A stereoselective reducing agent for reduction of cyclic ketones to thermodynaically more stable alcohols

摘要

In recent years, new developments in the area of stereoselective reduction of cyclic ketones have been exceptionally encouraging. Especially, the reagents de- veloped for conversion of cyclic ketones to the thermo- dynanmically less stable alcohols are extraordinary. However, although several useful reagents have been Devised for converting cyclic ketones to the thermody- Namically more stable alcohols, generally acceptable Synthetic methods for this conversion have still been Lacking.