A novel stereospecific route to (E)- and (Z)-(2-substituted-1,2-difluoroethenyl)stannanes

摘要

In the presence of 1.2-1.5 equiv of potassium fluoride, a variety of (E)- and (Z)-(2-substituted-1,2- difluoroethenyl)silanes reacted with tributyltin chloride in DMF at room temperature to 80 deg C to afford the corresponding stannanes in good yields with overall retention of configuration. These stannanes are useful intermediates for the introduction of the (E)- and (Z)-1,2-difluoroethylene unit into organic molecules.