A highly diastereoselectrive, tandem mukaiyama aldol-lactonization route to β-Lactones: application to a concise synthesis of the potent pancreatic lipase

摘要

β-Lactones (2-oxetanones) have recently emerged as important synthetic targets due to their occurrence in a variety of natural products, their utility as versatile synthetic intermediates, and their use as monomers for the preparation of biodegradable polymers.