General Method for the Synthesis of 8-Arylsulfanyl Adenine Derivatives

Huazhong He; Laura Llauger; Neal Rosen; Gabriela Chiosis

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General Method for the Synthesis of 8-Arylsulfanyl Adenine Derivatives

机译：合成8-芳基硫烷基腺嘌呤衍生物的通用方法

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摘要

We report a general method for the synthesis of 8-arylsulfanyl adenine derivatives using a mild protocol of coupling 8-mercaptoadenine with a variety of aryl iodides.

机译：我们报告了使用8-巯基腺嘌呤与各种芳基碘偶联的温和协议合成8-芳基硫烷基腺嘌呤衍生物的一般方法。

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来源
《The Journal of Organic Chemistry》 |2004年第9期|p.3230-3232|共3页
作者
Huazhong He; Laura Llauger; Neal Rosen; Gabriela Chiosis;
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作者单位

Departments of Medicine and Cell Biology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类有机化学;
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入库时间 2022-08-18 00:03:26

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1. Evaluation of 8-arylsulfanyl, 8-arylsulfoxyl, and 8-arylsulfonyl adenine derivatives as inhibitors of the heat shock protein 90 [J] . Llauger L, He HZ, Kim J, Journal of Medicinal Chemistry . 2005,第8期

机译：评估作为热激蛋白90抑制剂的8-芳基硫烷基，8-芳基硫氧基和8-芳基磺酰基腺嘌呤衍生物
2. An Efficient Copper-Catalyzed Microwave-Assisted S-Arylation towards the Synthesis of 8-Arylsulfanyl Adenines [J] . Weilin Sun, Pallav D. Patel, Ralph A. stephani, Synlett . 2011,第20期

机译：高效的铜催化微波辅助S-芳基化合成8-芳基硫烷基腺嘌呤
3. Synthesis of 2-(aminophenyl)adenine derivatives: a simple protocol using the classical iron powder/acetic acid reduction methodology [J] . Rocha A., Proenca M. F., Carvalho M. Alice Canadian Journal of Chemistry . 2020,第3期

机译：合成2-（氨基苯基）腺嘌呤衍生物：使用经典铁粉/醋酸还原方法的简单方案
4. Adenine and guanine derivative bases of purines and their corresponding nucleosides as corrosion inhibitors in 1M hydrochloric acid [C] . D.Y. Cruz Gonzalez, G. Negron Silva, D. Angeles Beltran, MES 26: Electrochemistry as a tool for sustainable development . 2011

机译：嘌呤的腺嘌呤和鸟嘌呤衍生物碱基及其相应的核苷在1M盐酸中的腐蚀抑制剂
5. Synthesis and use of 9-substituted adenine derivatives for studying Leishmania donovani 3'-nucleotidase. [D] . Szczepanik, Maciej Bernard. 2002

机译：9-取代的腺嘌呤衍生物的合成和用于研究利什曼原虫多诺万尼3'-核苷酸酶的用途。
6. Design Synthesis and Biological Activity Studiesof Istradefylline Derivatives Based on Adenine as A [O] . Yiyun Wang, Haojie Xu, Hongyi Wang, 2021

机译：设计合成和生物活性研究基于腺嘌呤的Istradefylline衍生物
7. Synthesis of 2-(aminophenyl)adenine derivatives: a simple protocol using the classical iron powder/acetic acid reduction methodology [O] . A. Rocha, M.F. Proença, M. Alice Carvalho 2020

机译：合成2-（氨基苯基）腺嘌呤衍生物：使用经典铁粉/醋酸还原方法的简单方案

General Method for the Synthesis of 8-Arylsulfanyl Adenine Derivatives

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