Palladium(0)-catalyzed highly regio- and stereoselective addition of organoboronic acids with 1,2-allenylphosphonates forming tri- or tetrasubstituted 1(E)-alkenylphosphonates

摘要

A highly regio- and stereoselective palladium(0)-catalyzed addition of organoboronic acids with 1,2-allenylphosphonates in the presence of HOAc forming tri- or tetrasubstituted 1(E)alkenylphosphonates is reported in this paper. The stereoselectivity is much higher than the reported cases. The effects of different R-1, R-2, and R-3 were studied. A mechanism of this reaction is proposed on the basis of our previous study.