Palladium-Catalyzed Arylation and Heteroarylation of Azolopyrimidines

摘要

A comparative study of the palladium-catalyzed arylation and heteroarylation of 5-bromoazolopyrimidines shows that aryl and electron-rich heteroaryl boronic acids gave higher yields than those obtained using the corresponding aryl and heteroaryl tributyl stannanes.In contrast,the reaction with electron-poor heteroaryl tributyl stannanes gave better results than the corresponding boronic acids.