Synthesis of Substituted Furoates from Acrylates and Aldehydes by Pd(OAc)_2/HPMoV/CeCl_3/O_2 System

摘要

A new synthetic method of substituted furoates from acrylates and aldehydes was developed by Pd-(OAc)_2 combined with molybdovanadophosphoric acid and Lewis acid under atmospheric dioxygen. The reaction was found to proceed through the palladium-catalyzed acetalization of acrylates with methanol followed by the reaction of the resulting acetals with aldehydes.