The effects of coxackievirus B3 infection on induction of ICAM-1 in cardiac myocytes and on lymphocte-myocyte adhesion

摘要

Objective: To observe the effects of coxackievirus B3(CoxB3) infection on-induction of intercellu- lar adhesion molecule-1 (ICAM-1) in cardiac myocytes and on lymphocyte-myocyte adhesion. Methods: ICAM- 1 expression on cultured neonatal rat cardiac myocytes infected by CoxB3 was determined through enzyme- linked immunosorbent assay (ELISA) analysis. Lymphocyte-myocyte adhesion was observed with adherence assay and monoclonal antibodies to adhesionmolecule inhibition.