CHANGES IN THE LEVEL OF BIOACTIVE COMPOUNDS IN PAULOWNIA TOMENTOSA FRUITS

摘要

The flavonoid and phenylpropanoid glycoside contents of Paulownia tomentosa Steud. fruits have been investigated in EtOH extracts obtained during the growing season. Using an HPLC-DAD system, we identified and quantified six C-geranyl flavanones: 3′-O-methyl-5′-hydroxydiplacone (1), 3′-O-methyl-5′-O-methyldiplacone (2), 3′-O-methyldiplacol (3), 3′-O-methyldiplacone (4), mimulone (5) and diplacone (6), and two phenylpropanoid glycosides acteoside (7) and isoacteoside (8). The levels of the flavonoids varied from minimums of 0.002-0.027% to maximums of 0.064-0.313% depending upon the individual flavonoid. The concentrations of the flavonoids increased during the 6-month period of the experiment in contrast to a decrease in the concentrations of the phenylpropanoid glycosides. The concentration of 8 was relatively low, fluctuating between 0.003 and 0.189%, whereas the concentration of 7 was the highest of all of the compounds investigated at 1.4%. The quantity of phenylpropanoid glycosides declined until June and then scarcely changed. Our data suggested that early summer was the appropriate time for harvesting P. tomentosa fruits if one is interested in the phenylpropanoid glycosides and autumn the best for the flavonoids. Our findings can be useful for obtaining the highest concentration of bioactive compounds of P. tomentosa fruits that can ensure a more effective study of the medicinal properties of these compounds and eventually a preparation of more efficient synthetic derivates. We have also examined the influence of the climatological condition on the total content of phenolic compounds.View full textDownload full textKeywordsflavonoids, HPLC, Paulownia tomentosa , phenolics, phenylpropanoid glycosides, ScrophulariaceaeRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/10826076.2011.547082