MRI装置更新に伴うVSRAD撮像シーケンスの検討

摘要

認知症は，65歳以上の老年者人口の約10％に見られ，その過半数はアルツハイマー型認知症（Alzheimer'sdisease；AD）であると考えられている．アルツハイマー型認知症では海馬および扇桃体，嗅内野皮質を中心とする内側側頭部の灰白賓客積の減少が初期から見られることが報告されている．これらの部位の容積を評価することが早期アルツハイマー型認知症における画像診断のポイントである．%In our institute, an MR apparatus, MAGNETOM VISION (Siemens) was replaced by ECHELON Vega (HITACHI). Z-score data acquired by MPRAGE (VISION) was compared with those by radio frequency-spoiled steady-state acquisition with rewinded gradient echo (RSSG) and gradient echo inversion recovery (GEIR) (ECHELON). For this study, ten normal volunteers were recruited and their data ware obtained within two months using both apparatuses. In addition, the difference of the contrasts of the images of these apparatuses was compared. There was a significant difference between Z-scores of MPRAGE and RSSG while there was no difference between MPRAGE and GEIR. As for the contrast, data of MPRAGE were similar to those of GEIR. To compare Z-scores acquired with MAGNTOM VISION (Siemens), it seems appropriate to use GEIR in ECHELON Vega.