Fabrication of Ag NPs/Zn-MOF Nanocomposites and Their Application as Antibacterial Agents

摘要

Three new nanocomposites consisting of Zn(II) metal-organic framework (Zn-MOF) and Ag nanoparticles (Ag NPs), designated as Ag NPs/Zn-MOFs1-3, based on the used doses of AgNO3, were fabricated. FT-IR (Fourier-transform infrared), PXRD (powder X-ray diffraction), SEM (scanning electron microscope), EDS (energy-dispersive X-ray spectroscopy) mapping, and TEM (transmission electron microscope) techniques were used for characterization of the prepared compounds. The obtained results have shown that the Ag NPs were successfully loaded on the Zn-MOF template. The spherical morphology of Ag NPs with diameter of 30-60 nm was confirmed through TEM analysis. The antibacterial activity of the synthesized compounds was then assessed againstStaphylococcus aureus,Bacillus subtilis,Pseudomonas aeruginosa, andEscherichia coli, using disc diffusion method. Among the studied composites, the one with higher dose of used AgNO3, i.e. Ag NPs/Zn-MOF1, had a broad-spectrum of antibacterial activity.