The immediate effects of the pill safety scare on usage of combined oral contraceptives in north east England

摘要

In October 1995, following advice from the Committee on Safety of Medicines, the Department of Health issued a press release concerning the use of seven brands of combined oral contraceptive pills. All pills carry an increased risk of venous thromboembolic events, though the absolute risk is low and considerably less than the health risks associated with an unwanted pregnancy or abortion. Recent studies suggest that newer pills, containing desogestrel or gestodene, are associated with higher rates of thrombosis. Doctors were recommended to review all women using the seven brands and advise them to change to lower risk types. Patients who were intolerant of the older types and without other risk factors for venous thrombosis might continue taking them, but on an informed basis. Through the media, women were advised not to stop using these brands, but to obtain medical advice, preferably before their current contraceptive cycle ended. Changes in oral contraceptive prescribing following the publicity suggest changes in the number of pill users.