Resistance to ciprofloxacin in pathogenic Enterobacteriaceae in England and Wales in 1996

摘要

In 1996, 6/100 of Escherichia coli from extraintestinal infections were resistant to ciprofloxacin with minimum inhibitory concentrations (MICs) ≥ 2 mg/l (high level resistance). Low level resistance (MIC 0.125-1 mg/1) was also identified in 7/100 of Salmonella typhi, 4/100 of S paratyphi A, and 4/100 of non-typhoidal salmonellas. However, resistance to ciprofloxacin was Rarely identified in shigellas. For E coli, Physicians should be aware that treatment Failures may occur when patients with Invasive illness are treated with cipro- Floxacin before the results of laboratory Sensitivity tests are available.