Expression of CD44 on bile ducts in primary sclerosing cholangitis and primary biliary cirrhosis

摘要

Aim-To examine expression of CD44, a transmembrane glycoprotein involved in lymphocyte homing and activation, in inflammatory liver diseases. Methods-Formalin fixed, paraffin em- Bedded tissues were obtained from nor- Mal, uninvolved liver from patients Undergoing partial hepatectomy for meta- Static carcinoma (9) and transplant hepa- Tectomy specimens from patients with Primary biliary cirrhosis (12), primary Sclerosing cholangitis (8), autoimmune Hepatitis (3), hepatitis C (3), and second- Ary sclerosing cholangitis (1).