Iodosylbenzene (PhIO) mediated synthesis of rose oxide from β- citronellol and its application for in situ rose oxide enrichment led valorization of citronella essential oil

摘要

Rose oxide occupies top rank among the volatiles of high olfactory significance. Naturally it occurs as a minor but precious constituent of essential oils obtained from Rosa damascene and Pelargonium spp. High cost and limited availability of natural rose oxide restricts its pervasive application in high-value perfumes. Therefore, synthetic rose oxide is produced on a much larger scale as a mixture of the four (-)-cis-,(+)-cis-, (-)-trans-, and (-)-trans-stereoisomers, having aroma profile similar to naturally occurring rose oxide. However, the methods reported in literature for preparation of synthetic rose oxide involve harsh reaction condition, use of toxic metals salts and non-renewable chemicals and solvents.