Halogenated monoterpenes having a cyclohexadienone from the red alga Poilieria homemanni

摘要

Five new ochtodane class monoterpenes have been isolated from two collections of the red alga Portieria hornemanni and their structures elucidated by spectroscopic analysis. These compounds contained 4,4-dimethylcyclohexa-2,5-dienone in common and differed in the C-2 side chain structure. Some of them showed mild cytotoxicity. Also discussed is the mechanism of the transformation of 2-chloro-1-hydroxyochtoda-3(8),5-dien-4-one, a related labile compound reported previously, into 4,5-dimethylbenzo[b]furan. [References: 10]