Synthesis and Characterization of Poly(biphenyl-2-yl p-styrenesulphonate) as Profungicide in Controlled Release Technique

摘要

A new fungicide controlled release formulation was prepared by the reaction of p-styrenesulphonyl chloride with biphenyl-2-ol (Dowicide A) as fungicide. The resulting monomer containing the fungicide was polymerized with benzoyl peroxide as initiator. The monomer and the polymer were identified by spectroscopic methods, and molecular weight of the polymer was determined by GPC. Also mp, Tg and Td of the polymer were identified by DSC. The release characteristic of the polymer was studied in neutral, alkaline, and acidic media. Also, the effect of the temperature on the release of bioactive agent (Dowicide A) was investigated. The hydrolysis data showed that the release rates are strongly dependent upon the pH of the medium and the temperature.