Combined analysis of HPV DNA, p16, p21 and p53 to predict prognosis in patients with stage IV hypopharyngeal carcinoma

Perle Ernoux-Neufcoeur; Mohammad Arafa; Christine Decaestecker; Anaëlle Duray; Myriam Remmelink; Xavier Leroy; Michael Herfs; Joan Somja; Christophe E. Depuydt; Philippe Delvenne

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Combined analysis of HPV DNA, p16, p21 and p53 to predict prognosis in patients with stage IV hypopharyngeal carcinoma

机译：HPV DNA，p16，p21和p53的组合分析可预测IV期下咽癌患者的预后

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Purpose We examined p16, p21 and p53 expression in combination with the presence of human papillomavirus (HPV) DNA as molecular markers to predict survival in patients with stage IV hypopharyngeal squamous cell carcinoma (HSCC).

机译：目的我们结合人乳头瘤病毒（HPV）DNA作为分子标志物检测了p16，p21和p53的表达，以预测IV期下咽咽鳞癌（HSCC）患者的生存。

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《Journal of Cancer Research and Clinical Oncology》 |2011年第1期|p.173-181|共9页
作者
Perle Ernoux-Neufcoeur; Mohammad Arafa; Christine Decaestecker; Anaëlle Duray; Myriam Remmelink; Xavier Leroy; Michael Herfs; Joan Somja; Christophe E. Depuydt; Philippe Delvenne;
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正文语种 eng
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Human papillomavirus – PCR – Typing – Hypopharynx – Carcinoma;

机译：人乳头瘤病毒– PCR –打字–下咽–癌;

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1. Combined analysis of HPV DNA, p16, p21 and p53 to predict prognosis in patients with stage IV hypopharyngeal carcinoma. [J] . Ernoux Neufcoeur P, Arafa M, Decaestecker C, Journal of Cancer Research and Clinical Oncology . 2011,第1期

机译：HPV DNA，p16，p21和p53的联合分析可预测IV期下咽癌患者的预后。
2. The absence of high-risk HPV combined with specific p53 and p16INK4a expression patterns points to the HPV-independent pathway as the causative agent for vulvar squamous cell carcinoma and its precursor simplex VIN in a young patient. [J] . Kruse AJ, Bottenberg MJ, Tosserams J, International journal of gynecological pathology: Official journal of the International Society of Gynecological Pathologists . 2008,第4期

机译：没有高风险的HPV与特定的p53和p16INK4a表达模式相结合，表明HPV依赖性途径是年轻患者外阴鳞状细胞癌及其前体单纯性VIN的病因。
3. Pre‐treatment CD CD 8 + + tumour‐infiltrating lymphocyte density predicts distant metastasis after definitive treatment in patients with stage III III / IV IV hypopharyngeal squamous cell carcinoma [J] . Ono T., Azuma K., Kawahara A., Clinical otolaryngology: official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery . 2018,第5期

机译：预处理CD CD 8 + +肿瘤浸润淋巴细胞密度预测III III阶段III阶段患者的定期治疗后的远端转移术后性抗性鳞状细胞癌
4. The clinical efficacy of transfusion of cytokine-induced killer cells combined with chemotherapy and XiaoJi decoction in patients with stage IIIB/IV non-small cell lung cancer [C] . Liuning Li, Jiaying Liu, Xiaoshu Chai, IEEE International Conference on Bioinformatics and Biomedicine . 2014

机译：细胞因子诱导的杀伤细胞输注结合化学疗法和消积汤治疗IIIB / IV期非小细胞肺癌的临床疗效
5. Subgroup analysis based on prognostic and predictive gene signatures for adjuvant chemotherapy in early-stage non-small-cell lung cancer patients [D] . Pluta, Dustin. 2015

机译：基于预后和预测基因特征的亚组分析用于早期非小细胞肺癌患者的辅助化疗
6. Combined analysis of HPV DNA p16 p21 and p53 to predict prognosis in patients with stage IV hypopharyngeal carcinoma [O] . Perle Ernoux-Neufcoeur, Mohammad Arafa, Christine Decaestecker, -1

机译：HPV DNAp16p21和p53的组合分析可预测IV期下咽癌患者的预后
7. Combined analysis of HPV DNA, p16, p21 and p53 to predict prognosis in patients with stage IV hypopharyngeal carcinoma. [O] . Ernoux-Neufcoeur, Perle, Arafa, Mohammad, Decaestecker, Christine, 2011

机译：HPV DNA，p16，p21和p53的组合分析可预测IV期下咽癌患者的预后。

Combined analysis of HPV DNA, p16, p21 and p53 to predict prognosis in patients with stage IV hypopharyngeal carcinoma

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