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首页> 外文期刊>Journal of Antimicrobial Chemotherapy >Effect of transcriptional activators RamA and SoxS on expression of multidrug efflux pumps AcrAB and AcrEF in fluoroquinolone-resistant Salmonella Typhimurium
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Effect of transcriptional activators RamA and SoxS on expression of multidrug efflux pumps AcrAB and AcrEF in fluoroquinolone-resistant Salmonella Typhimurium

机译:转录激活因子RamA和SoxS对耐氟喹诺酮类鼠伤寒沙门氏菌多药外排泵AcrAB和AcrEF表达的影响

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摘要

Objectives Multidrug resistance (MDR) including fluoroquinolone resistance in Salmonella Typhimurium can result from overexpression of efflux pumps. We examined the mechanisms of fluoroquinolone resistance among in vitro-induced ciprofloxacin-resistant Salmonella Typhimurium mutants, LTL and LTH, derived from laboratory strain LT2.
机译:目的鼠伤寒沙门氏菌的多药耐药性(MDR)包括氟喹诺酮耐药性可能由外排泵的过表达引起。我们检查了源自实验室菌株LT2的体外诱导的环丙沙星耐药鼠伤寒沙门氏菌突变体LTL和LTH中氟喹诺酮耐药的机制。

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