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首页> 外文期刊>Journal of Antimicrobial Chemotherapy >Attenuation of Pseudomonas aeruginosa virulence factors and biofilms by co-encapsulation of bismuth–ethanedithiol with tobramycin in liposomes
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Attenuation of Pseudomonas aeruginosa virulence factors and biofilms by co-encapsulation of bismuth–ethanedithiol with tobramycin in liposomes

机译:铋乙二硫醇与妥布霉素共包裹在脂质体中对铜绿假单胞菌毒力因子和生物膜的减弱

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摘要

Objectives This study examined the activities of tobramycin and bismuth against quorum sensing, virulence factors and biofilms of Pseudomonas aeruginosa by co-encapsulating the agents in liposomes in order to achieve greater delivery of the agents.
机译:目的本研究通过将药物共包裹在脂质体中来检查妥布霉素和铋对铜绿假单胞菌的群体感应,毒力因子和生物膜的活性,以实现更大的药物传递。

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  • 来源
    《Journal of Antimicrobial Chemotherapy》 |2010年第4期|p.684-693|共10页
  • 作者单位

    The Novel Drug & Vaccine Delivery Systems Facility, Department of Chemistry and Biochemistry, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada;

    The Novel Drug & Vaccine Delivery Systems Facility, Department of Chemistry and Biochemistry, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada|Medical Sciences Division, Northern Ontario School of Medicine, Lakehead University, 955 Oliver Road, Thunder Bay, Ontario, P7B 5E1, Canada;

    The Novel Drug & Vaccine Delivery Systems Facility, Department of Chemistry and Biochemistry, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada|Sudbury Regional Hospital, Regional Cancer Center, 41 Ramsey Lake Road, Sudbury, Ontario, P3E 5J1, Canada;

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