The New -Amino Acid N~ω-Hydroxy-nor-L-arginine: a High-Affinity Inhibitor of Arginase Well Adapted To Bind to Its Manganese Cluster

摘要

The new α-amino acid, nor-NOHA, is the most potent inhibitor of arginase (both from rat liver or mouse macrophages) reported so far. Its use for better understanding the physiological roles of arginases in vitro and in vivo is underway.