Detection of quinolone-resistant Neisseria gonorrhoeae in urogenital specimens with the use of real-time polymerase chain reaction

摘要

In a recent issue of this journal, Jabeen et al.1 added to the growing body of literature describing the worldwide emergence of fluoroquinolone resistant Neisseria gonorrhoeae (QRNG).2–5 Although fluoroquinolones are a first-line treatment for syndromic urethritis in Peru,6 the presence of QRNG has not been documented in that country. However, considering the relatively recent emergence of QRNG, resistant NG strains might have recently become prevalent. Recently, a number of molecular methods have been developed recently for the detection of QRNG.7–9 These assays might facilitate detection and surveillance of QRNG by allowing the testing of urogenital samples without the need of culture. The goal of our study was to use a real-time polymerase chain reaction (PCR) assay to conduct a pilot study to assess the presence of QRNG among a small group of persons at high-risk in urban, coastal Peru.