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首页> 外文期刊>International journal of imaging systems and technology >In Vivo Correlation Between Semi-Quantitative Hemodynamic Parameters and K~(trans) Derived from DCE-MRI of Brain Tumors
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In Vivo Correlation Between Semi-Quantitative Hemodynamic Parameters and K~(trans) Derived from DCE-MRI of Brain Tumors

机译：半定量血流动力学参数与脑肿瘤DCE-MRI得出的K〜（trans）的体内相关性

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摘要

Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) has become more and more widely applied in cancer diagnosis and treatment follow-up. Without complicated calculation, a semiquantitative parameter - modified initial area under the curve (mlAUC_c) - was proposed for better correlation with volume transfer constant (K_(trans)) by computer simulation. In this study, we aim to further investigate the correlation between mlAUC_c and K~(trans) in clinical. A total of 10 patients with brain tumors participated in this study and images were acquired by using a 3-Tesla clinical MR scanner. The results showed that mlAUC_c was highly correlated with K~(trans) with the correlation coefficient of 0.913. Although the ideals of K~(trans) and mlAUCc are different, mlAUC_c does the trick for brain tumors evaluations in DCE-MRI. It reveals that mlAUC_c could be an alternative for physiological condition evaluation in DCE-MRI.
机译：动态对比度增强（DCE）磁共振成像（MRI）已越来越广泛地应用于癌症的诊断和治疗随访中。无需复杂的计算，就可以通过计算机模拟提出半定量参数-曲线下的初始面积（mlAUC_c），以更好地与体积转移常数（K_（trans））相关。在这项研究中，我们旨在进一步研究mlAUC_c和K〜（trans）在临床上的相关性。共有10名脑肿瘤患者参加了这项研究，并使用3-Tesla临床MR扫描仪获取了图像。结果表明，mlAUC_c与K〜（trans）高度相关，相关系数为0.913。尽管K〜（trans）和mlAUCc的理想是不同的，但mlAUC_c可以帮助DCE-MRI评估脑肿瘤。它表明mlAUC_c可以作为DCE-MRI中生理状况评估的替代方法。

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    Chen Chin-Feng; Hsu Ling-Wei; Lui Chun-Chung; Lee Chen-Chang; Weng Hsu-Huei; Tsai Yuan-Hsiung; Liu Ho-Ling;

  • 作者单位

    Department of Diagnostic Radiology, Chang Gung Memorial Hospital, ChiaYi Branch, College of Medicine and School of Medical Technology, ChiaYi, Taiwan;

    Department of Medical Imaging and Radiological Sciences, Chang Gung University,Taoyuan, Taiwan;

    Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan;

    Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan;

    Department of Diagnostic Radiology, Chang Gung Memorial Hospital, ChiaYi Branch, College of Medicine and School of Medical Technology, ChiaYi, Taiwan;

    Department of Diagnostic Radiology, Chang Gung Memorial Hospital, ChiaYi Branch, College of Medicine and School of Medical Technology, ChiaYi, Taiwan;

    Department of Medical Imaging and Radiological Sciences, Chang Gung University,Taoyuan, Taiwan;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    magnetic resonance imaging; dynamic contrast enhanced; initial area under the curve; volume transfer constant;

    机译：磁共振成像动态对比度增强;曲线下的初始面积;体积转移常数;
  • 入库时间 2022-08-17 13:37:12

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