DuPont demonstrates leadership and innovation in the field of early life nutrition

摘要

DUPONT NUTRITION & BIOSCIENCES recently released the findings of a first-time new study showing the effects Care4U™ 2'-FL had on dental caries-associated bacterium Streptococcus mutans. Previously, HMOs have not been studied for their effects on oral bacteria, but as HMOs are increasingly being added to infant formula, it is important to evaluate effects on oral microflora and potential impact on oral health. "Human milk is known to contain factors that protect against caries, so we were interested to know how HMOs, and especially 2'-FL, affect S. mutans, one of the most studied bacteria related to dental caries, said Johanna Hirvonen Ph.D., Senior Scientist DuPont Nutrition & Biosciences. "This study was a collaboration between University of Turku, Institute of Dentistry and DuPont Nutrition & Biosciences. We evaluated the ability of S. mutans to grow on 2'-fucosyllactose (2'-FL) in comparison to galacto-oligosaccharides (COS), lactose, and xylitol. The effects of 2'-FL, COS, lactose, and xylitol on adhesion properties of S. mutans were also evaluated. While this study was done under in vitro conditions, it showed the differences between the studied carbohydrates, especially in s. mutans growth."