Preliminary screening of the antibacterial effect of the pigmented squid ink extracts against methicillin resistant Staphylococcus aureus (MRSA)

摘要

This present investigation is to assess the antibacterial property of the squid ink extracts from Loligo duvauceli against methicillin resistant Staphylococcus aureus [MRSA]. MRSA strain was isolated and was characterized by standard microbiological methods. Genotypic detection of mecA gene was done by PCR. Isolated strain was further subjected to antibacterial bioassay with the crude extracts of squid ink obtained using various solvents. Hexane extract scores a promising antimicrobial effect against MRSA, with trace activity by ethyl acetate extract and no activity by other solvent extracts. MIC value was determined as 2.5mg/ml.