体幹部FDG-PET画像の経時差分処理に基づくコンピュータ支援診断システムの開発

摘要

The purpose of this study is to develop a technique for the computer-aided diagnosis (CAD) system in torso FDG-PET images. We constructed the CAD system that integrates two technologies of temporal subtraction and score image production. The doctor evaluated the effectiveness of integrated system of the two techniques. In the experiment, 21 normal cases, 11 good cases, and 26 malignant cases were employed all with temporal changes. The appropriateness of the temporal-subtraction image processing inclusion was evaluated by three stages as "appropriate", "unclear", and "inappropriate". As a result, the evaluations of appropriateness were 54 pairs (85%) for appropriate, 0 pairs (0%) for unclear, and nine pairs (15%) for inappropriate. It was found from this qualitative evaluation that the system developed was able to show the temporal changes of most of the diseased areas appropriately.%本研究では，FDG-PET画像の支援診断を目的として，スコア画像の作成に関する技術と経時差分像技術を統合したシステムを構築し，医師による経時差分画像の有効性の評価実験を行った．経時変化のある症例として，正常21例，良性11例，悪性26例を用いて，1人の医師による評価実験を行った．差分像処理の適切さを，「適切」，「わからない」，「不適切」の3段階で評価した結果，適切に経時変化を示した組は54組（85％），わからないが0組，不適切が9組（15％）であった．この定性的な結果から，本システムは病変部の経時変化の多くを適切に表示できたといえる．