The (TAAAA)_n microsatellite polymorphism in the SHBG gene influences serum SHBG levels in women with polycystic ovary syndrome

摘要

BACKGROUND Hyperandrogenaemia is a common feature of polycystic ovary syndrome (PCOS). The sex hormone-binding globulin (SHBG) gene was proposed as being a PCOS candidate gene. A possible influence of the microsatellite polymorphism (TAAAA)_n in the SHBG gene on serum SHBG levels in PCOS patients was investigated.