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Lipid droplets: a classic organelle with new outfits

机译:脂质滴:具有新装的经典细胞器

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摘要

Lipid droplets are depots of neutral lipids that exist virtually in any kind of cell. Recent studies have revealed that the lipid droplet is not a mere lipid blob, but a major contributor not only to lipid homeostasis but also to diverse cellular functions. Because of the unique structure as well as the functional importance in relation to obesity, steatosis, and other prevailing diseases, the lipid droplet is now reborn as a brand new organelle, attracting interests from researchers of many disciplines.
机译:脂质滴是实际上存在于任何类型细胞中的中性脂质的储库。最近的研究表明,脂质滴不仅是脂质斑点,而且不仅是脂质稳态的主要贡献者,而且还是多种细胞功能的主要贡献者。由于其独特的结构以及与肥胖症,脂肪变性和其他常见疾病相关的功能重要性,脂质滴如今重生为崭新的细胞器,吸引了许多学科研究人员的兴趣。

著录项

  • 来源
    《Histochemistry and Cell Biology》 |2008年第2期|263-279|共17页
  • 作者单位

    Department of Anatomy and Molecular Cell Biology Graduate School of Medicine Nagoya University 65 Tsurumai Showa Nagoya 466-8550 Japan;

    Department of Anatomy and Molecular Cell Biology Graduate School of Medicine Nagoya University 65 Tsurumai Showa Nagoya 466-8550 Japan;

    Department of Anatomy and Molecular Cell Biology Graduate School of Medicine Nagoya University 65 Tsurumai Showa Nagoya 466-8550 Japan;

    Department of Anatomy and Molecular Cell Biology Graduate School of Medicine Nagoya University 65 Tsurumai Showa Nagoya 466-8550 Japan;

    Department of Anatomy and Molecular Cell Biology Graduate School of Medicine Nagoya University 65 Tsurumai Showa Nagoya 466-8550 Japan;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Lipid droplet; Lipid ester; Phospholipid; Cholesterol; PAT protein; Caveolin;

    机译:脂质滴;脂质酯;磷脂;胆固醇;PAT蛋白;小窝蛋白;

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