Clinical Study With Computerized Axial Manomerty of Lower Esophageal Sphincter Function Berore And After Fundoplication For Gastroesophageal Reflux Disease

摘要

The functional effects of surgery for gastroesophageal reflux disease (GERD) were examined with computerized axial manometry (CAM). Twenty-four-hour esophageal pH monitoring and CAM analysis of lower esophageal function were performed in 5 healthy volunteers (control group) and in 16 patients with GERD before and after fundoplication. The effect of gastric wall expansion on CAM volume was also examined after insufflation with 500 to 1,500 ml of air.