Indium(III) Chloride-Catalyzed Conversion of {[(Benzyloxy)carbonyl]amino}-Substituted Sulfones with 2-[(Trimethylsilyl)oxy]furan: A Facile Access to -Butenolactone Derivatives Containing a Protected Amino Group†

摘要

Treatment of {[(benzyloxy)carbonyl]amino}-substituted sulfones 1 with 2-[(trimethylsilyl)oxy]furan (2) in the presence of InCl₃ as a catalyst at room temperature produced the -butenolactone derivatives 3 and 4 containing a protected amino group (Scheme 1). The products were formed in high yields (81–92%) within 3–10 h favoring the anti-isomer 3.