Electronic epidemiology and the risk of cardiovascular disease in inflammatory rheumatic diseases

摘要

Cardiovascular disease (CVD) has emerged as a major cause of morbidity and mortality in patients with inflammatory rheumatic diseases, notably systemic lupus erythematosus and rheumatoid arthritis. The pathophysiology of premature and accelerated atherosclerosis in those patients is multifactorial, involving traditional cardiovascular risk factors, systemic and vascular chronic inflammation and adverse effects of drugs, such as cor-ticosteroids and non-steroidal anti-inflammatory drugs. Considering the premature and accelerated atherosclerosis in chronic rheumatic disease, guidelines for the management of rheumatic inflammatory disorders recommended that patients should be screened for CVD, with aggressive management of traditional cardiovascular risk factors to try to reduce this excess vascular risk.