Relation of serum cytokine concentrations to cardiovascular risk factors and coronary heart disease

摘要

Conclusions-This study confirms that many of the phenomena with which C reactive protein is associated, are also associated with serum levels of cytokine, which may be the mechanism. Objective-To determine whether serum Concentrations of the cytokines tumour Necrosis factor α (TNFα) and interleukin 6 (IL-6), which regulate C reactive protein, are associated with cardiovascular risk fac- tors and prevalent coronary heart disease. Design-A population based cross sec- Tional study. Subjects and methods-198 men aged 50 to 69 years were part of a random population sample drawn from south London.