Measuring quality of life in opioid-induced constipation: mapping EQ-5D-3 L and PAC-QOL

摘要

Background In health economic evaluations, quality of life should be measured with preference-based utilities, such as the EuroQol 5 Dimension 3-level (EQ-5D-3L). Non-preference-based instruments (often disease-specific questionnaires) are commonly mapped to utilities. We investigated if the relationship observed between the Patient Assessment of Constipation Quality of Life (PAC-QOL) and the EQ-5D-3L in patients with chronic idiopathic constipation (CIC) also applies in opioid-induced constipation (OIC).