processes for treating and preventing opioid-induced constipation using oral methylnaltrexone compositions

摘要

Patent Summary of the Invention: "Methods for treating and preventing opioid-induced constipation using oral methylnaltrexone compositions". Methods for treating or preventing opioid-induced constipation by administering oral methylnaltrexone compositions are disclosed herein. the processes are based, at least in part, on identifying individuals who are particularly susceptible to such treatment and the optimal dosages of such oral compositions to treat or prevent opioid-induced constipation and also to minimize the occurrence of associated adverse events. to such treatment.