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Evaluation of bioactive compounds potential and antioxidant activity of brown, green and red propolis from Brazilian northeast region

机译:巴西东北地区棕色,绿色和红色蜂胶的生物活性化合物潜力和抗氧化活性评估

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摘要

The aim of the present study was to determine the contents of bioactive compounds present in brown, green and red species of propolis cultivated in the Brazilian northeast states of Alagoas and Sergipe. The contents of phenolic compounds, flavonoids and antioxidant activity (DPPH, ABTS, FRAP, ORAC) were determined. Identification and quantification of phenolic and flavonoid compounds were performed by using UHPLC-QqQMS/MS system. The results revealed high contents of total phenolics and flavonoids. Among the three species, the antioxidant potential had higher capacity in the red propolis. The presence of some of bioactive compounds viz. acacetin, artepellin C, eriodictyol, gallic acid, isorhamnetin, protocatechuic acid, vanillin and vanillic acid in Brazilian red propolis is reported for the first time in this work. Positive correlation between total phenolics versus the FRAP and ORAC methods was established which led to conclusion that antioxidant activity of propolis is mainly due to its phenolic compounds.
机译:本研究的目的是确定在巴西东北部阿拉戈斯州和塞尔希培州种植的蜂胶的棕色,绿色和红色物种中存在的生物活性化合物的含量。测定酚类化合物,类黄酮的含量和抗氧化活性(DPPH,ABTS,FRAP,ORAC)。酚和类黄酮化合物的鉴定和定量通过使用UHPLC-QqQMS / MS系统进行。结果显示总酚和类黄酮的含量很高。在这三个物种中,红色蜂胶中的抗氧化剂潜力更高。一些生物活性化合物的存在。这项工作中首次报道了巴西红蜂胶中的醋酸乙酰醋西丁酯,artepellin C,eriodictyol,没食子酸,异鼠李素,原儿茶酸,香草醛和香草酸。建立了总酚与FRAP和ORAC方法之间的正相关关系,从而得出结论,蜂胶的抗氧化活性主要归因于其酚类化合物。

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