Detection, occurrence and effects of endocrine disruptors in Luxembourgish food items

摘要

PCB's (polychlorinated biphenyls) and atrazine, a herbicide, can act as endocrine disrupters, molecules perturbing hormonal Systems, resulting e.g. in fertility-problems. These xenobiotics can be very persistent in the environment and accumulate in the food-chain. The objective of the present in-vestigation was to quantify PCB's, atrazine and main degradation products (desethyl-and deisopropylatrazine) in food and water in Luxembourg. In addition, transcrip-tomic and proteomic effects of PCB's and atrazine were studied.