Estimated daily intake of plasticizers in 1-week duplicate diet samples following regulation of DEHP-containing PVC gloves in Japan

摘要

Duplicate hospital diet sampled obtained over 1 week in 2001 were analysed to estimate the daily intake of plasticizers and the results were compared with those obtained in 1999. The plasticizers quantified in this study were: dibutyl phthalate, butylbenzyl phthalate (BBP), di(2-ethylhexyl) phthalate (DEHP), diisononyl phthalate (DINP), di(2-ethylhexyl) adipate (DEHA), diisononyl adipate (DINA) and O-acetyl tributyl citrate (ATBC). Dipropyl, dipentyl, dihexyl and dicyclohexyl phthalate were also analysed but not detected. The analytical procedure for this follow-up study was essentially the same as in the previous one. Detection limits were 0.1-15.6 ng g~(-1) for each plasti-cizer. One-week duplicate diet samples provided by three hospitals in three remote prefectures of Japan were analysed as individual meals. DEHP was detected at 6-675 ng g~(-1) in 62 of 63 meals, significantly lower levels compared with those detected in 1999. Levels of DEHA and DINP also decreased. The mean intake of plasticizers estimated from all samples was 160 μg DEHP day~(-1), 12.5 μg DEHA day~(-1), 4.7 μg DINP day~(-1) and 3.4 μg BBP day~(-1). Levels of DINA were relatively high in meals from one hospital: in those meals, the average daily intake was 1338 μg day~(-1). Those of ATBC were also higher in meals from another hospital: the average daily intake was 1228 μg day~(-1). The sources of DINA and ATBC can be ding-film or sausage packaging.