σ~B and the σ~B-dependent arlRS and yabJ-spoVG loci affect capsule formation in Staphylococcus aureus

摘要

The alternative transcription factor σ~B of Staphylococcus aureus affects the transcription of the cap gene cluster, required for the synthesis of capsular polysaccharide (CP), although this operon is lacking an apparent σ~B-dependent promoter. Regulation of cap expression and CP production in S. aureus strain Newman was shown here to be influenced by σ~B, the two-component signal transduction regulatory system ArlRS, and the yabJ-spoVG locusrnto different extents.