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Management of intramedullary spinal cord abscess: experience with four cases, pathophysiology and outcomes

机译:髓内脊髓脓肿的处理:4例经验,病理生理学和预后

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Intramedullary spinal cord abscess (ISCA) in children is extremely a rare infection of the central nervous system (CNS); and probably a devastating neurological condition. Clinical awareness of patients at risk is crucial for early diagnosis and intervention; as this entity is one of the treatable conditions of paraparesis. Association with congenital neuro-ectodermal abnormality in children is frequent. This pathology highlights the importance of complete neurological checks of infants as a part of their routine physical examination and early management of patients with congenital dermal sinus, prophylactic surgical resection of such a congenital anomaly is recommended by most authors to prevent serious infections of the CNS. However, once the abscess is established; immediate surgical drainage along side adequate antibiotics should be instituted. This may guarantee improving neurological outcome. In this communication, the authors present their experience with four cases of ISCA in children treated successfully with surgical drainage, intravenous antibiotics and neuro rehabilitation between 2001 and 2006 and discuss their results. We concluded that early diagnosis and treatment is essential; before a devastating mechanico-vascular insult of the spinal cord is established from rapid formation of the abscess and a swift expansion of the spinal cord within the limited intraspinal space.
机译:儿童髓内脊髓脓肿(ISCA)是中枢神经系统(CNS)的一种极为罕见的感染。并可能造成毁灭性的神经疾病。对有风险的患者的临床认识对于早期诊断和干预至关重要。因为这个实体是截瘫的可治疗条件之一。与儿童先天性神经外胚层异常相关。这种病理学突显了对婴儿进行全面神经系统检查的重要性,这是其常规体格检查和对先天性皮肤窦患者进行早期治疗的一部分,大多数作者建议对此类先天性异常进行预防性手术切除,以防止严重感染中枢神经系统。但是,一旦脓肿建立;应立即进行手术引流,并给予足够的抗生素。这可以保证改善神经学结果。在此交流中,作者介绍了2001年至2006年间成功通过外科引流,静脉抗生素和神经康复治疗的4例ISCA患儿的经验,并讨论了他们的结果。我们得出结论,早期诊断和治疗至关重要。在脓肿迅速形成和脊髓在有限的椎间隙内迅速扩张后,就建立了破坏性的脊髓机械性血管损伤。

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